The Antagonist of All Antagonists

Iago is the best example of an antagonist possibly in the history of literature. He doesn't care about anyone but himself. Everything he does is self-serving. "Here, stand behind this bulk, straight will he come. Wear thy good rapier bare, and put it home (Act 5, Scene 1)." In this instance, Iago is preparing Roderigo to kill Cassio. Roderigo is another poor schmuck Iago has convinced to do hid dirty work (i.e. kill Cassio to get him out of the way so that he can become lieutenant). Iago has also tricked Othello into thinking Desdemona cheated on him with Cassio to get revenge for Othello supposedly sleeping with Emelia. Really, the story revolves around Iago's deceptions.